Evidence synthesis – Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence
From the latest Science for ME weekly update
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19 #auscovid19
Leukocyte telomere length and telomerase activity in Long COVID patients from Rio de Janeiro, Brazil
"The Long COVID patients were found to have an increase in LTL [leukocyte telomere length]."
From the latest Science for ME weekly update
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2
@auscovid19 #auscovid19
UPDATED: #BC #SARSCoV2 variants.
Only 42 & 47 samples for weeks of 2/9 & 2/16
Of the 47,
XEC.*: 34% (
52.4%; 
33.9%)
LP.8.1.*: 27.7% ( 11.9% §; 15.3%)
PA.1: 14.9% ( 11.9%; <2%)
https://ratnegative.tumblr.com/BCVariants #COVID19
----------
Of the samples collected in B.C. on these weeks, the prevalence of significant variants/lineages are as follows:
- 2/16 - 2/22 - (47 samples; 4% threshold)
• XEC.* (incl. XEC.1, ".2.2, ".11.1): 34%
• JN.1.11.1.* †: 59.6%
→ LP.8.1.* (incl. LP.8.1.1, ".8.1.4): 27.7%
→ KP.3.* (only KP.3.1.1.*): 31.9%
→ KP.3.1.1.* (incl. MC.1.*, ".10.1.*, ".24, ".31): "
→ PA.1 (= MC.10.1.1.1): 14.9%
† 1 KP.2.18 sample counted as Other
- 2/9 - 2/15 - (42 samples; 4% threshold)
• XEC.* (incl. XEC.1, ".2.*, ".9): 52.3%
• JN.1.11.1.* §: 59.3%
→ LP.8.1.* (only LP.8.1.1, ".8.1.4 counted) §: 11.9%
→ KP.3.* (only KP.3.1.1.*): 33.3%
→ KP.3.1.1.* (incl. MC.1.3, ".10.1, ".26.1): "
→ PA.1: 11.9%
§ 1 LP.8.1 sample counted as Other
X.X.* in text = X.X & descendants.
X.X.* in graph = all descendants of X.X, except for ones that have their own segment of the week’s bar. Please see "Notes on Usage" section.
Press release for a new UK study:
"Nearly one in ten unsure if they have Long Covid. Almost 5% have the condition and socially disadvantaged groups are most affected"
https://www.eurekalert.org/news-releases/1076866
Free paper:
https://onlinelibrary.wiley.com/doi/10.1111/hex.70202
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19 #auscovid19
This #LongCovidAwarenessDay I’m reflecting on how many people have been let down by governments, public health & medical establishments
How Covid has been downplayed, airborne spread ignored & vaxx and relax strategies pushed for the sake of capitalism
How many have Long Covid because of this?
Those of us who were disabled before the pandemic could see this wave of chronic illness coming - and many of us have been screaming from the top of our lungs the last 5 years.
Begging people not to take their health for granted & to wear a mask and protect themselves.
Warning them that there are no do-overs once you become chronically ill. Unfortunately very few people are listening - and many won’t understand the true devastation of #LongCovid until it directly impacts them. At which point it’ll be too late.
Despite seeing these waves of disability as an inevitable consequence of “let er rip” Covid strategy - one thing I did not see coming was how many people would willingly embrace not only ableism - but full on eugenics.
People in my own life who were previously kind & supportive have become cruel and angry. The masks have been ripped off. They don’t hesitate to tell me that they blame me for the restrictions placed on them in the early days of Covid.
That they will never again allow their freedoms to be infringed on in the name of protecting the vulnerable. One even went as far as to say “you’ve been sick for years - just die already.”
People who say these things don’t understand what disabled ppl understand all too well - your health is not a permanent state.
Everyone will become disabled eventually - some earlier than others. Many who think they’re invulnerable are already vulnerable and don’t even know it
Yet rather than adapting behaviour and pushing for a new normal that makes the world safe for everyone - most temporarily abled people have instead doubled down on hateful eugenics talking points and want us to stay home forever (or worse - die). It needs to stop.
Covid is airborne and we all share the air. “You do you” individualism is quite literally killing people. We need to start caring about the air we share as this will lead to a healthier society for everyone.
Until then we need to mask up. It’s easy, incredibly effective & it might save someone’s life. At the very least you will know you didn’t contribute to another person’s suffering - and you will be drastically reducing your own odds of getting Long Covid. It’s worth it.
https://www.disabledginger.com/p/i-dont-know-anyone-with-long-covid
It’s International Long Covid Awareness Day, and my latest article looks at the reasons why people believe they don’t know anyone with Long Covid.
We desperately need increased visibility into this debilitating chronic illness so that we can raise awareness and fund treatments, mitigations and cures.
Anyone can get Long Covid. It’s not limited to ‘only the vulnerable’ or those who had a severe initial infection.
This disease does not discriminate. Even people with asymptomatic initial infections have found themselves disabled by Long Covid.
It’s time we start processing the trauma of the pandemic and stop living in denial.
We are in the middle of a mass disabling event, and the longer it takes us to admit that, the more people will be harmed.
Let’s spread the word that the only way to avoid Long Covid is to avoid getting Covid in the first place.
Wear a mask. Stay home when sick. Clean and ventilate the air.
When we all agree to care about the air we share, we can begin to bring about real change.
https://www.disabledginger.com/p/i-dont-know-anyone-with-long-covid
Ensitrelvir Prevents #COVID19 Infection as Post Exposure Prophylaxis
> Japan-based Shionogi presented results for its investigational antiviral, ensitrelvir, that demonstrated a 67% reduction in the risk of developing COVID-19 in uninfected individuals treated after exposure, compared to a placebo at day 10
March 15 is #LongCovidAwarenessDay
Everything you don't want to know about #COVID:
COVID is #airborne.
It's not "mild."
Infection damage is cumulative.
It makes you more susceptible to other infections and diseases.
There is no cure for #longCOVID.
The #pandemic is not over.
Wearing a #mask reduces transmission.
Source: whn.global
"SARS-CoV-2 spike RNA- and SARS-CoV-2-related inflammation persist in the epipharynx for more than six months post infection. Although no expression of the SARS-CoV-2 spike protein in the epipharynx was evident in these patients with long COVID, genetic analysis revealed activation of [...] the SARS-CoV-2 signalling pathway in epithelial cells, B cells, and pDCs. This aligns with theories that even nonactive viral fragments may possess biological significance. This persistence of inflammation, identified for the first time at the genetic level, highlights the epipharynx as a critical site for continual immune responses in long COVID patients, suggesting that residual viral antigens may contribute to the chronic symptoms experienced"
"After the administration of EAT [epipharyngeal abrasive therapy] once a week for 3 months, the expression of viral RNA disappeared in patients 1 and 2. Patient 3 presented a substantial reduction in viral RNA expression; although complete clearance was not achieved, a marked decrease was observed."
"observed dysregulation of immune and ciliary pathways" - might explain the chronic nonsmoker cough that seems more common now
"These findings suggest that T cells still play a subtle role in the immune dysregulation observed in patients with long COVID. Collectively, these findings indicate that interactions among pDCs, B cells, plasma cells, and T cells contribute to the chronic inflammation and immune dysregulation characteristic of patients with long COVID"
"In the pre-EAT state of long COVID Patient 2, the tissue surface was predominantly covered by ciliated epithelium (Cluster 7). In contrast, following treatment, the ciliated epithelium was no longer observed, and a new cluster of squamous epithelial cells (Cluster 12) emerged"
"EAT effectively eliminates the inflamed ciliated epithelium in patients with long COVID and induces the formation of squamous cells with high barrier function"
https://www.nature.com/articles/s41598-025-92908-7
thanks @MEActNOW
German spy agency believed CoVid-19 likely started in a laboratory in Wuhan.
The widely accepted theory is that Covid-19 emerged in bats and then jumped to humans, most likely through another animal, or "intermediary host."
As time worn on, scientists have not found a virus in either bats or another animal that matches the genetic make-up of Covid-19, leading some to doubt the theory.
#Pandemic #CoVid19 #Asian #Health #Virus #PublicHealth #SARSCov2
Cause of post-#COVID inflammatory shock in children identified: Reactivation of the Epstein-Barr virus appears to cause the rare condition #MISC. The findings, uncovered by a team from #CharitéBerlin & the DRFZ, have now been published in #Nature.
These insights open the door to new treatment methods, potentially not limited to MIS-C.
#CharitéPaper #Science #Research #Medicine #EBV #PIMS #SARSCoV2 #COVID19 #corona
@nature.portfolio
Ursache für Entzündungsschock bei Kindern nach #Corona aufgeklärt: Die als #PIMS bekannte seltene Erkrankung wird offenbar durch eine Reaktivierung des Epstein-Barr-Virus ausgelöst. Das zeigt ein Team von #CharitéBerlin & DRFZ jetzt in #Nature.
Die Erkenntnisse eröffnen neue Therapiemöglichkeiten, möglicherweise nicht nur für PIMS.
#CharitéPaper #Wissenschaft #Forschung #Medizin #EBV #MISC #SARSCoV2 #COVID19
@nature.portfolio
Some people reportedly experience Long COVID remission from a "remission biome protocol" https://www.remissionbiome.org/about/protocol-overview
The waiting list: https://www.remissionbiome.org/patients/join-the-protocol
Today marks the five year anniversary of Covid being declared a pandemic. Some things I want people to remember:
The threat is not gone. People are still dying and becoming disabled every single day
COVID is airborne. It’s always been airborne. Droplet transmission was pushed incorrectly & then doubled down on for economic reasons. If governments admit it’s airborne, they have to spend money upgrading air quality and providing respirators etc.
The only way to avoid Long Covid is to not get Covid.
A well fitted respirator like an N95 offers excellent personal protection
Mask mandates belong in healthcare
If you’re not masking for your patient, you’re abdicating your responsibility to do no harm
It costs nothing to open a window and it will improve ventilation and reduce odds of viral spread. Air purifiers work well too
COVID is a social justice issue. Masks, tests, air filters, paid time off… these things all cost money. The disease disproportionately impacts those who are most vulnerable and multiple marginalized
Repeat infections don’t make you stronger. They don’t give you immunity. They actually harm your brain, heart and immune system. They’re also NOT inevitable
Kids are harmed by COVID too. They need the adults to protect them. We need clean in schools and on school buses
We went “back to normal” for capitalism. It wasn’t because it was safe. It wasn’t because there was a cure. Governments and those in power Are willing to sacrifice us to keep end stage capitalism afloat a little longer
Repeat infections are NOT inevitable. We can still curb the spread. We don’t have to accept constant sickness and disability as our new normal.
May we be in a much better place five years from now than we are today.
If you know someone suffering from Long Covid, reach out to them. Ask them how you can support them. Remind them they’ve not been forgotten. Wear a mask for them. They are counting on you.
(USA)
#MEAction @meactnet and the Patient-Led Research Collaborative @patientled
have written an open letter to HHS director Robert F. Kennedy, Jr. calling for him to reinstate the #LongCOVID Advisory Committee.
@longcovid
#PwLC #PostCovidSyndrome #LC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #COVID_19 #SARSCoV2 @novid #novid #CovidIsNotOver #auscovid19
The Guardian ‘We’re losing decades of our life to this illness’: #longCovid patients on the fear of being forgotten
https://www.theguardian.com/society/2025/mar/02/were-losing-decades-of-our-life-to-this-illness-long-covid-patients-on-the-fear-of-being-forgotten
"Five years on from March 2020, millions of people still face debilitating symptoms, with huge repercussions on public health and productivity. But politicians are starting to pretend the pandemic never happened"
@longcovid
#PwLC #PASC #postcovid
#CovidBrain
@covid19 #COVIDー19 #COVID19 #COVID #SARSCoV2 #novid #CovidIsNotOver
COVID: Heartbreaking - report: @lbc.co.uk 
How many more years must pass before we fully recognise the reality of this airborne pathogen?
How many must risk being infected with #SARSCoV2 before we demand better infection control measures and technological solutions?
https://www.lbc.co.uk/news/uk/heartbreaking-scenes-bereaved-uk-tribute-victims-covid-19/
COVID: Something is in the air, still.
How many more years must pass before we fully recognise the reality of this airborne pathogen?
How many must risk being infected with #SARSCoV2 before we demand better infection control measures and technological solutions?
https://www.mirror.co.uk/news/uk-news/covid-19-day-reflection-thousands-34825874
